CRC 010

The purpose of the study is to help to understand how safe, effective, and tolerable different doses of the study treatment QCZ484 are in people living with mild to moderate hypertension.

CRC 011

We are doing this study to learn more about the benefits and safety of treatment of an experimental drug called baxdrostat in combination with dapagliflozin for treating patients with CKD and high blood pressure. We also want to better understand CKD and the health problems that come with it.

JCCT 223

This study is being done to learn more about maridebart cafraglutide (MariTide [formerly AMG 133]) in people with heart failure (HF) and obesity in addition to their routine medical care.

JCCT 236

The purpose of this research is to test a new investigational vaccine, VAX-31. VAX-31 causes the body to make antibodies (germ fighters) in adults who previously received a pneumococcal vaccine, and potentially increases the amount of antibodies to the strains in common with the previous pneumococcal vaccine.

JCCT 235

This study will evaluate the safety and efficacy of tirzepatide for the treatment of participants with MASLD who are at increased risk of major adverse liver outcome (MALO) events (high-risk MASLD).

JCCT 215

The purpose of this study is to find out if the study vaccine is safe and how your immune system responds to it.

JCCT 228

This study is testing an investigational drug called GIGA-2339. We want to see if it is safe and easy to handle. We also want to see how your immune system reacts to it, how your body processes it, and what effect it has on your health.

JCCT 239

The purpose of this study is to learn about the effects of cadisegliatin (also called “TTP399”) compared to placebo to find out if or how much cadisegliatin may reduce the episodes of low blood sugar (hypoglycemia) in T1DM, or lower HbA1c, and to see how people with T1DM feel and do when taking cadisegliatin (how the study drug is tolerated).

CRC 018

We are doing this study to learn more about a new drug called AZD7760 when it is given as an intravenous (IV; into the vein) infusion to healthy adults (Phase I) or adults with end‑stage kidney disease who are on hemodialysis with a central venous catheter (Phase IIa).

CRC 016

We are doing this study to learn more about how effective, safe and tolerable an experimental drug called balcinrenone is when used in combination with dapagliflozin for treating patients with heart failure and impaired kidney function and also to better understand the studied disease and associated health problems.