The purpose of this research is to evaluate in gout patients who have been taking allopurinol regularly, how will addition of an investigational drug ABP-671 affects how allopurinol and its active substance (oxypurinol) are absorbed and metabolized in the body.
We are doing this study to learn more about the benefits and safety of treatment of an experimental drug called baxdrostat in combination with dapagliflozin for treating patients with CKD and high blood pressure. We also want to better understand CKD and the health problems that come with it.
The purpose of this study is to learn about the effects of cadisegliatin (also called “TTP399”) compared to placebo to find out if or how much cadisegliatin may reduce the episodes of low blood sugar (hypoglycemia) in T1DM, or lower HbA1c, and to see how people with T1DM feel and do when taking cadisegliatin (how the study drug is tolerated).
The purpose of this study is to find out if the study vaccine is safe and how your immune system responds to it.
This study is being conducted to find out if the study drug prevents major heart and circulation problems in people who are at high risk for heart disease and have high blood pressure.
This study is designed to provide the needed safety and immunogenicity data in healthy adult population to support rapid deployment of the SUDV vaccine against an ongoing or future outbreak of the Sudan strain of Ebola.
This study will evaluate the safety and efficacy of tirzepatide for the treatment of participants with MASLD who are at increased risk of major adverse liver outcome (MALO) events (high-risk MASLD).
This study is being conducted to find out if the study drug prevents major heart and circulation problems in people who have or are at high risk for heart disease and have high blood pressure.
We are doing this study to learn more about treatments that could reduce the risk of developing heart failure, reduce the risk of death from cardiovascular causes and also to better understand the studied disease and associated health problems.
This study is focused on participants who have diabetic kidney disease. The aim of this study is to see how safe and effective the study drugs are.
Please note that this clinical trial will use an investigational drug product that has not yet been approved for use outside of clinical trials. The safety and efficacy of the investigational drug product have not been fully evaluated by Regulatory Authorities and has not received marketing authorization in any country.
