JCCT 204

We are doing this study to learn more about an investigational vaccine called IVX-A12. An investigational vaccine is one that is not approved by the United States Food and Drug Administration (FDA).

The IVX-A12 study vaccine is being developed to prevent disease caused by 2 respiratory viruses, called respiratory syncytial virus (RSV) and human metapneumovirus (hMPV), in adults who are at least 60 years old. The main purpose of this study is to see how safe IVX-A12 is and how the immune system responds to IVX-A12 compared with another study vaccine (Arexvy®), which is approved by the FDA to prevent RSV disease in adults who are at least 60 years old.

CRC 001

A Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study to Assess the Efficacy and Safety of Baxdrostat in Participants with Uncontrolled Hypertension on Two or More Medications including Participants with Resistant Hypertension. We are doing this study to learn more about an investigational drug called Baxdrostat for treating high blood pressure that is not responding well enough to current treatment.

We are doing this study to learn more about an investigational drug called Baxdrostat for treating high blood pressure that is not responding well enough to current treatment. Hypertension is a serious condition that can cause several complications and may reduce your life expectancy if not treated appropriately. Baxdrostat has already been tested in participants with difficult-to-control high blood pressure in earlier research called “Phase 2” studies. Based on what we have learned in those studies about the potential for Baxdrostat to improve blood pressure levels, this Phase 3 study has been developed.

JCCT 157

The purpose of this study is to collect blood (serum) or plasma from healthy people who have not been exposed to N. meningitides bacteria and do not have antibodies to the bacteria. Plasma and serum are the liquid parts of blood (that is, blood without the cells in it). The main difference between plasma and serum is that plasma has proteins that help blood clot, and serum does not. An antibody is a substance made by the immune system to fight infection. Both serum and plasma contain important components called complement proteins. These proteins together with the antibody are important for the immunity against infection-causing bacteria.

This study aims to collect blood (serum) or plasma that has suitable complement from donors for use in laboratory tests to measure antibody responses of subjects participating in studies where vaccines against N. meningitidis are administered. It’s hard to find donors who have human complement that can be used for these tests. Many adults have been exposed to N. meningitidis and already have antibodies in their blood, which prevent them from being eligible to donate plasma or blood (serum) for this study.

JCCT 179

PRE-SCREENING NOW!

Coronaviruses are a large family of viruses that cause illness ranging from the common cold to more severe diseases, such as Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). Coronaviruses are zoonotic, meaning they are transmitted between animals and people.

An outbreak of the coronavirus disease (COVID-19) caused by the 2019 novel coronavirus SARS-CoV-2 began in Wuhan, Hubei Province, China in December 2019 and has spread throughout China and to over 215 other countries, territories, and areas, including the United States.

Vaccines serve to prepare your immune system for fighting illnesses. Certain cells of the immune system produce antibodies (special proteins) that recognize viruses and other pathogens (things that cause disease) and prevent them from causing illness. Currently, there are several vaccines that have been authorized or approved for the prevention of COVID-19 disease. However, as new strains of the virus