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This study is being conducted to find out if the study drug prevents major heart and circulation problems in people who are at high risk for heart disease and have high blood pressure.
This study is being conducted to find out if the study drug prevents major heart and circulation problems in people who are at high risk for heart disease and have high blood pressure.
This study is designed to provide the needed safety and immunogenicity data in healthy adult population to support rapid deployment of the SUDV vaccine against an ongoing or future outbreak of the Sudan strain of Ebola.
This study will evaluate the safety and efficacy of tirzepatide for the treatment of participants with MASLD who are at increased risk of major adverse liver outcome (MALO) events (high-risk MASLD).
This study is being conducted to find out if the study drug prevents major heart and circulation problems in people who have or are at high risk for heart disease and have high blood pressure.
We are doing this study to learn more about treatments that could reduce the risk of developing heart failure, reduce the risk of death from cardiovascular causes and also to better understand the studied disease and associated health problems.
This study is focused on participants who have diabetic kidney disease. The aim of this study is to see how safe and effective the study drugs are.
Please note that this clinical trial will use an investigational drug product that has not yet been approved for use outside of clinical trials. The safety and efficacy of the investigational drug product have not been fully evaluated by Regulatory Authorities and has not received marketing authorization in any country.
This study is testing an investigational drug called GIGA-2339. We want to see if it is safe and easy to handle. We also want to see how your immune system reacts to it, how your body processes it, and what effect it has on your health.
This study is being done to learn more about maridebart cafraglutide (MariTide [formerly AMG 133]) in people with heart failure (HF) and obesity in addition to their routine medical care.
We are doing this study to learn more about a new drug called AZD7760 when it is given as an intravenous (IV; into the vein) infusion to healthy adults (Phase I) or adults with end‑stage kidney disease who are on hemodialysis with a central venous catheter (Phase IIa).
We are doing this study to learn more about how effective, safe and tolerable an experimental drug called balcinrenone is when used in combination with dapagliflozin for treating patients with heart failure and impaired kidney function and also to better understand the studied disease and associated health problems.